Knowledge Center · Hormones

Thyroid (TSH, T3, T4)

Endogenous hormonePrescription therapy existsRequires monitoring

Thyroid hormones set the body's metabolic rate, affecting energy, weight, mood, temperature, and heart rate. Thyroid problems are common and treatable.

Overview

The thyroid gland produces T4 and T3, regulated by TSH from the pituitary. Together they set metabolic rate — influencing energy, body weight, temperature, mood, skin, hair, and heart rate. Both underactive (hypothyroid) and overactive (hyperthyroid) states are common and well-characterized.

What It Does

  • Sets basal metabolic rate.
  • Influences energy, weight regulation, and temperature.
  • Affects mood, cognition, heart rate, and skin/hair.

What Affects It

  • Autoimmune conditions (e.g., Hashimoto's, Graves').
  • Iodine and selenium status.
  • Pregnancy and certain medications.
  • Stress and severe illness (which alter readings).

Measuring It

Thyroid status is assessed by blood tests — typically TSH first, then free T4 and free T3, plus thyroid antibodies when autoimmune disease is suspected. Interpretation is clinical, not a single number.

Optimization & Therapy

Hypothyroidism is commonly and effectively treated with thyroid hormone replacement under a provider, with dose guided by labs and symptoms. Hyperthyroidism has its own established treatments. Both require diagnosis and monitoring.

Considerations & Risks

  • Symptoms overlap with many other conditions — testing matters.
  • Over- or under-treatment both cause problems.
  • Requires periodic lab monitoring.

Who May Wish to Discuss It With Their Provider

Fatigue, weight change, temperature intolerance, or mood changes warrant thyroid evaluation by a licensed provider.

Frequently Asked Questions

What's the first thyroid test?

Usually TSH, often with free T4; free T3 and antibodies are added based on the picture.

Can thyroid issues cause fatigue and weight gain?

Yes — an underactive thyroid commonly does, which is why testing is worthwhile when symptoms persist.

Want to understand your own levels?

If you'd like help applying this information to your own health, schedule a consultation with the Bearing team.

Request a Consultation

References

  • American Thyroid Association guidelines.
  • PubMed: 'hypothyroidism management'.

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Educational disclaimer. This page is general education, not medical advice, and does not diagnose or treat disease or guarantee outcomes. Hormone evaluation and any therapy must be individualized and managed by a licensed provider.